@crawford,
Which version of SignalScope Pro you are running?
Which operating system are you running it on?
On which device (Mac, iPhone, iPad, which model)?
The gain setting should be set according to your specific needs. Depending on the specific hardware you are using, a lower gain (-24 dB) should allow the mic to measure higher sound levels before clipping. A higher gain (0 dB) should be used when you want to measure lower sound levels.
I'm not sure what you mean by "blow the mic out," but changing the input gain won't harm the mic. When you say that it doesn't work, what exactly do you mean? Is there no signal at all? Does the signal appear distorted?